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Proteoliposomes

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Synthetic Cell Models

Protocell models with functions inaccessible in nature

JACS Au  2024, 4, 1841–1853 (Link)

Proteoliposomes

Proteoliposomes to understand lipid biosynthesis & regulation

Journal of Lipid Research  2022, 63, 100282 (Link)

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Giant unilamellar

vesicles

10 µm

Proteoliposomes

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Synthetic or Xeno Nucleic Acids (XNAs)

Transforming an archaeal DNA polymerase to catalyze the formation of internucleotidyl N–P bonds

XNAs (like N-P-linked polymers) can serve as new-generation therapeutics with biochemically fortified backbones.  

ACS Chemical Biology  2022, 17, 1924–1936 (Link)

Proteoliposomes

RNA Sensors Made of DNA Aptamers

Fluorescent light-up DNA aptamers for sensing nucleic acid targets in biological media

MiRNA detection with single nucleotide specificity; toward identifying genetic or epigenetic cancer biomarkers.

Bioorganic & Medicinal Chemistry  2022, 69, 116909 (Link)

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