Chem 308: Organic Chemistry II

This course is intended for undergraduate students who have successfully completed Chem 307 and are willing to learn some of the complex topics (selected examples are shown below). A general understanding of introductory organic chemistry is required. 

Principles of Peptide bond-forming reactions... 

Catalytic C-C Bond Formation...

Carbohydrates...

6.0

6.5

5.5

4.0

5.0

4.5

ppm

 Chem 488 / 544: Special Topics in Biological Chemistry 

Synthetic Organic Techniques in Chemical Biology: This course is intended for advanced undergraduate students (488) and graduate students (544) who are willing to learn chemical biology and the applications of organic chemistry within. A firm background in synthetic organic chemistry is required. A general understanding of biological chemistry is expected.

Informational Polymers... Fundamental properties of DNA and RNA... Chemical and Biophysical implications of these properties... Nanoscale machines made of DNA and RNA... 

DNA duplex

RNA duplex

J. Am. Chem. Soc (2015), p6373.

Antibiotics... Some macrolide antibiotics bind the Large Ribosomal Subunit and block the peptide exit tunnel. Hansen, et al. Mol. Cell (2002), p117.

Bioluminescence...

Images from Marine Biol. Lab. & 

Angew. Chem. Int. Ed. (2009), p5590.