Organic synthesis of designer molecules with programmed functionality
Courtesy of Dorsa Ebrahimi (development of probes, prodrugs, and small molecule therapeutics). Photo credit: Zeynep Yaslan
Small molecules and noncoding RNAs can turn E. coli into whole cell biosensors for inorganic redox species.
The project details and long-term vision can be found in C&EN and EurekAlert!.
Courtesy of Sarah Cho and Liming Wang (experiment design and data collection)
We investigate nitrative stress in murine models of acute lung injury (with Debra Laskin & Andrew Gow at Rutgers Pharmacy)
3D Rendering of Live Lung Tissue Upon Nitrative Stress
Courtesy of Tushar Aggarwal (experiment design, data collection, and 3D video) and Alyssa Bellomo (lung tissue preparation)
Using our surface functionalization methods, we can modulate the morphology and cytoskeletal organization of mammalian cells
Mouse preosteoblasts (MC3T3-E) on a silicon surface untreated (left) vs treated (right)
Human umbilical vein endothelial cells (HUVEC) on a titanium surface untreated (left) vs treated (right)
Courtesy of Zhaojun Jia (experiment design and data collection)
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